What is meant by the amino acid pool?
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According to Charles E. Ophardt (2003), The “nitrogen or amino acid pool” is a grand mixture of amino acids available in the cell derived from dietary sources or the degradation of protein. Since proteins and amino acids are not stored in the body, there is a constant turnover of protein. Some protein is constantly being synthesized while other protein is being degraded. For example, liver and plasma proteins have a half-life of 180 days or more, while enzymes and hormones may be recycled in a matter of minutes or hours.
Each day, some of the amino acids are catabolized producing energy and ammonia. The ammonia is converted to urea and excreted from the body and represents a drain on the nitrogen pool.
A nitrogen balance is achieved by a healthy person when the dietary intake is balanced by the excretion of urea wastes. If nitrogen excretion is greater than the nitrogen content of the diet, the person is said to be in negative nitrogen balance. This is usually interpreted as an indication of tissue destruction. If the nitrogen excretion is less than the content of the diet, a positive nitrogen balance indicates the formation of protein